Francis C K Chiu Selected Research

Enzymes

1/2020	Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria.
12/2016	A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria.

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Francis C K Chiu Research Topics

Disease

6	Malaria 01/2021 - 08/2004
1	Alzheimer Disease (Alzheimer's Disease) 03/2019
1	Parasitemia 01/2019
1	Chagas Disease (American Trypanosomiasis) 12/2013
1	Melanoma (Melanoma, Malignant) 02/2010
1	Neoplasms (Cancer) 02/2010
1	Colonic Neoplasms (Colon Cancer) 10/2009

Drug/Important Bio-Agent (IBA)

2	1,2,4-trioxaneIBA 01/2021 - 03/2011
2	Dihydroorotate DehydrogenaseIBA 01/2020 - 12/2016
2	EnzymesIBA 01/2020 - 12/2016
2	DSM265IBA 01/2020 - 12/2016
2	artemisinin (artemisinine)IBA 08/2009 - 08/2004
2	Antimalarials (Antimalarial Agents)IBA 08/2009 - 08/2004
1	PyrrolesIBA 01/2020
1	pyrimidineIBA 01/2020
1	Peptides (Polypeptides)IBA 03/2019
1	Copper-64IBA 03/2019
1	Amyloid (Amyloid Fibrils)IBA 03/2019
1	fenarimolIBA 12/2013
1	OligosaccharidesIBA 02/2010
1	phosphomannopentaose sulfateIBA 02/2010
1	GlycosidesIBA 02/2010
1	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2009
1	pixantrone (BBR 2778)IBA 10/2009
1	PeroxidesIBA 08/2009
1	Heme (Haem)IBA 08/2004
1	Artemether FDA Link 08/2004
1	ArtesunateIBA 08/2004
1	ArtemisininsIBA 08/2004

Therapy/Procedure

1	Therapeutics 01/2020
1	Oral Administration 01/2019
1	Drug Therapy (Chemotherapy) 08/2004